Lion's Mane




Protect your brain with Lion’s Mane.

Lion’s Mane is a non-psychoactive, functional, and legal mushroom that stimulates memory, focus and cognition.

Lion’s Mane is also widely known as the Smart Mushroom for its brain-enhancing capabilities and our best-selling natural nootropic for this reason.

Human Pro Lion’s Mane is the most potent commercially available Lion’s Mane extract in the world.

  • Stimulates memory & focus
  • Stimulates Nerve Growth Factor (NGF)
  • Stimulates your natural ability to learn & acquire new information
  • Stimulates energy levels
  • Can improve anxiety and depression
  • Can provide strong immune support
  • Extreme potency (20:1)
  • All active components are heavily concentrated & bioavailable

Quality guaranteed: All important active compounds in the extracts are specified and their bioavailability is guaranteed.

90 vegetarian capsules, 30-45 day supply

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What is Lion’s Mane?

Known scientifically as Hericium Erinaceus, Lion’s Mane is a potent mushroom that supports and promotes brain functioning and cognition.

Note: This listing should and can not be construed as a list of medical claims.

Lion’s Mane best practices

Recommended daily dose:

The daily recommended dosage of 3 capsules can be taken all at once or throughout the course of your day and is ideal for daily use.

Our unique 20:1 dual extraction Lion’s Mane capsule contains:

  • 420 mg per capsule (100% extract, no fillers & GMO-free)

Lion’s Mane precautions include:

Please consult your doctor before supplementing with Lion’s Mane and specifically under these circumstances:  If you are pregnant and/or breastfeeding, or if there is the presence of bleeding disorders, clotting disorders, low blood pressure, or if you are expecting to have surgery in 2 weeks or less. Always consult your doctor before undertaking any mushroom protocol.

Lion’s Mane best practices can also include:

Some of our clients enjoy starting their day with Lion’s mane, other sources suggest taking it throughout the day. In order to maximize its benefits, be sure to track how you are feeling. Take note of what is happening now, before starting with these extracts. Observe and perhaps even start a journal to log any changes in cognition, focus, creativity,  mood, memory, or dreaming? 

For example, perhaps digestive issues are greatly improved? Are there any noticeable improvements in the appearance and tone of your skin? Are you feeling more rested in the morning upon waking? Logging how your body and mind feel (before, during, and after) is a deeply valuable tool when taking any nootropic, superfood, or adaptogen.

Worth noting; some of our clients report vivid dreams when taking Lion’s Mane. Due to the mushrooms’ ability to mitigate inflammation and therefore reduce depletion of serotonin, dreams can be more engaging and vivid, but not disturbing. At all times, remember that you know your body and mind better than anyone and must always follow the protocol that is ideal for you, at this time.

*This information is for informational purposes only and has not been reviewed or approved by EFSA. Human Pro supplements are not medicines and should never be used as a substitute for regular medication.


What are the benefits of Lion’s Mane? 

Medicinal mushrooms bring many well-being benefits and certain strains come with added superpowers. Lion’s Mane is sought after for its cognitive enhancements and digestive soothing properties.


Is Lion’s Mane addictive?

No. Lion’s mane mushrooms are not addictive. 


Does Lion’s Mane give energy?

Lion’s Mane can increase concentration and improve focus. Its effect on overall inflammation may improve your energy levels but it is not an adaptogen like Cordyceps are.


Does Lion’s Mane get you high?

Lion’s Mane has no psychoactive compounds. It is the unlocked alkaloids that improve NGF (nerve growth factor) and therefore provide cognitive benefits.


When is the best time to supplement with Lion’s Mane?

Both Lion’s Mane and cordyceps can reset your circadian rhythm and might induce an energizing effect when taken in the morning after a good night’s sleep, with or without food.


What are the concentration ratios of our Lion’s Mane?

  •  Concentrated 20:1 extraction
  •  More than 50% of active components
  •  40% polysaccharides


  • Is our product from mycelium or the fruiting body of the Lion’s Mane mushroom?

  Our Lion’s Mane is grown from the fruiting body and using organic methods.


  • How long can I supplement with Lion’s Mane?

There is no toxic level dose for Lion’s Mane mushrooms in addition to not being habit-forming in any way. Continue to pay attention to how you feel when supplementing and when not, notice how your body responds and supplement accordingly.



1. Could protect against dementia like Alzheimer’s or Parkinson’s disease

Lion’s Mane has two main bioactive compounds: Hericenones and Erinacines.

Hericenones assist the brain in producing more Nerve Growth Factor (NGF) and Erinacines helps with the production of new neurons, also known as neurogenesis (Source).

Lion’s Mane has been shown to be very effective in stimulating the creation of NGF in the brain. Once the blood-brain barrier has been crossed, Lion’s Mane is shown to stimulate the release of NGF, which treats and prevents nerve damage.

In general, when your brain grows older, its ability to form new connections decreases which explains why your mental capacity declines when you get older. Therefore, the production of more NGF in your brain could possibly help to relieve symptoms of neurodegenerative diseases, such as Alzheimer’s and Parkinson’s disease. This was already shown in animal studies that successfully protected mice from a progressive memory loss disease like Alzheimer’s (SourceSourceSourceSource).

2. May lower anxiety and depression

Almost 30 percent of people in today’s society experience symptoms of anxiety or depression (Source). While there are many factors that play a role in causing anxiety or depression, one important factor is chronic inflammation in the body.

Studies show that Lion’s Mane has strong anti-inflammatory effects that can reduce the symptoms of anxiety and depression (SourceSource).

In addition, other studies show that Lion’s Mane supports the regeneration of brain cells and improves the functioning of the hippocampus. The hippocampus is a region of the brain which deals with processing memories and emotions. It is believed that a better functioning hippocampus may explain a relief in anxiety, irritation, and depression (SourceSource).

It is important to note that while studies already look very promising, more human studies are needed to completely confirm these benefits.

3. May speed up recovery from nervous system injuries

Studies show that Lion’s Mane extract may help to speed up recovery from injuries to the brain (stroke), spinal cord, and other nerves in the body. It does this by stimulating the growth and repair of nerve cells in the body (SourceSourceSource).

In a study conducted on rats, Lion’s Mane has been shown to reduce the time that is needed to recover from a nervous system injury by 23 to 41 percent (Source).

In another study, high doses of lion’s mane mushroom extract given to rats immediately after a stroke helped decrease inflammation and reduce the size of stroke-related brain injury by 44% (Source).

However, as these studies look very promising, more human studies are needed to confirm this benefit for humans.

4. Could reduce heart disease risk

The most often named factors for heart disease are obesity, high triglycerides, large amounts of oxidized cholesterol, and an increased tendency to get blood clots.

Recent studies have shown that Lion’s Mane extract can improve some of these factors and could therefore reduce the risk of heart disease.

For example, Lion’s Mane has been shown to lower obesity and triglycerides. One study in rats and mice shows that Lion’s Mane extract has improved fat metabolism and lowered triglyceride levels in the body (Source). Another one saw 27% lower triglyceride levels and 42% less weight gain after a month (Source).

Furthermore, a study found out that Lion’s Mane extract can lower the levels of oxidation of cholesterol in the bloodstream of the body (Source). The oxidation of cholesterol molecules causes them to become harder and therefore increases the risk of heart disease. And Lion’s Mane contains Hericenone B which decreases the rate of blood clotting in your bloodstream, which also lowers the risk of a stroke or heart attack (Source).

5. Helps manage diabetes symptoms

Diabetes disease prevents your body from properly regulating the sugar levels in your blood. Your body constantly regulates the levels of sugar in your blood, and if you constantly have high blood sugar levels, it might cause issues with your kidney, loss of nerves in the hands and feet, and loss of vision.

It is shown that Lion’s Mane mushroom has the power to improve blood sugar levels and also to help with lowering symptoms in the body (Source).

In multiple animal studies, it was shown that Lion’s Mane can lower blood sugar levels in normal and diabetic mice. This effect was even significant with low doses (SourceSource). Lion’s Mane has the power the block the activity of certain enzymes (alpha-glucosidase) that break down carbs in your digestive tract (Source). If this enzyme is blocked, the body is unable to digest and absorb carbs as effectively, which results in lower blood sugar levels.

Also, Lion’s Mane may have the power to lower nerve pain in your hands and feet. This was tested for six weeks on mice with nerve damage, who got Lion’s Mane on a daily basis, and as a result showed significantly less pain, lower blood sugar levels, and more antioxidants in their system (Source).

6. Improves your cognition

Besides stimulating the production of NGF, Lion’s Mane is also widely used in order to enhance focus and mental alertness. Users report a clearer state of mind and experience less brain fog. This is why many people use Lion’s Mane in order to achieve better focus and enter into deeper flow states. This helps with being more productive at work or studying.

In a human trial study, they let older people with mild cognitive impairment consume Lion’s Mane on a daily basis, for four months in a row. During this period they saw significant improvements in their mental capacity, and after they stopped supplementing Lion’s Mane, the benefits disappeared (Source).


*This information is for informational purposes only and has not been reviewed or approved by EFSA. Human Pro supplements are not medicines and should never be used as a substitute for regular medication.


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